Incidence and prevalence of primary sclerosing cholangitis in a defined adult population in sweden
نویسندگان
چکیده
منابع مشابه
The prevalence, incidence and natural history of primary sclerosing cholangitis in an ethnically diverse population
BACKGROUND Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease often associated with inflammatory bowel diseases (IBD). Current epidemiological data are limited to studies of predominantly Caucasian populations. Our aim was to define the epidemiology of PSC in a large, ethnically diverse US population. METHODS The Northern California Kaiser Permanente (KP) databas...
متن کاملIncidence, prevalence, and natural history of primary sclerosing cholangitis in the United Kingdom
Primary sclerosing cholangitis (PSC) is a rare obliterative fibrotic condition of the bile ducts. We assessed PSC epidemiology and natural history within the UK Clinical Practice Research Datalink (CPRD).Incidence and natural history of PSC were evaluated in a retrospective cohort study using linkage of CPRD, Hospital Episode Statistics, and Office for National Statistics data. Data from age, s...
متن کاملControversies in Primary Sclerosing Cholangitis
• MRCP should be used as the initial investigation to diagnose PSC as it has similar accuracy without the invasiveness of ERCP. • Patients with a high clinical suspicion of PSC but with normal cholangiogram should undergo liver biopsy to exclude small duct PSC. Likewise, liver biopsy is indicated if an overlap with autoimmune hepatitis is suspected. In this case, treatment with corticosteroids ...
متن کاملPregnancy in primary sclerosing cholangitis.
BACKGROUND There is a paucity of data on fertility or pregnancy in patients with primary sclerosing cholangitis (PSC). OBJECTIVE To assess fertility in PSC by comparing the number of children in a large cohort of PSC patients to healthy controls and to investigate the outcome of pregnancy, as well as the influence of pregnancy on the disease course. DESIGN Case series. SETTING Germany. ...
متن کاملCholangiocarcinoma in primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. Cholangiocarcinoma (CC) occurs in 10 20% of patients with PSC. The prognosis for CC is poor, even after liver transplantation. It is of great importance to identify PS...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2010
ISSN: 0270-9139
DOI: 10.1002/hep.23678